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How to perform test

 hs-CRP/CRP | Wizbiotech 

On this page

  1. Video tutorial
  2. Supplies overview
  3. Text instructions
  4. Results evaluation
  5. Disposal instructions


Video tutorial for hs-CRP/CRP by Wizbiotech




Supples overview

  • 1x CRP Test Cassette
  • 1x Fixed-Volume Capillary Pipette
  • 1x Sterile Lancet
  • 1x Alcohol Swab
  • 1x Swab
  • 1x Buffer Solution Tube
  • 1x Igloo Reader
  • 1xWizbiotech Adapter

Text instructions


STEP 1: Prepare and Disinfect the Sampling Area

Lay out all kit components. Disinfect the fingertip with the alcohol swab and let it dry.

Warm up your finger before sampling. To improve blood flow and make collection easier, gently warm your hand for a few minutes. You can use a warm cloth, soak in warm water, or rub your hands together.


STEP 2: Perform a Fingerstick

Use the sterile lancet to puncture the side of the fingertip. Gently massage the finger to form a blood drop.


​

STEP 3: Remove the first droplet of blood

Wipe away the first drop of blood with a clean tissue or sterile gauze before collecting the sample. This ensures accuracy and prevents contamination. 


STEP 4: Collect exactly 10 µL of blood

The blood will fill the pipette automatically by capillary action. 

Important: Ensure the blood sample is collected properly.


​

Important 

Ensure that the pipette is completely filled without any bubbles. This will ensure that you obtain the exact 10 µL of blood required.

 


STEP 5: Transfer Blood into Buffer

Pierce the foil with the pipette containing capillary blood to then mix the contents.


STEP 6: Mix the blood with the buffer

Shake 5–10 times to ensure proper mixing.


Important 

Make sure the blood and buffer are well mixed and show a uniform color.


STEP 7: Prepare the test cassette

Add 2 drops of the mixed sample into the test cassette


​

STEP 8: Start using the device

Turn on the device using the power button located underneath.

Once the device is on, press “New Measurement” and enter the required data to begin the test.


STEP 9: Insert the test cassette into the reader

Insert the test cassette into the reader — the measurement will start automatically.


STEP 10: Wait 3 minutes



STEP 11: Result is ready

When the timer ends, your result will be displayed on the screen.


​

Scan QR for quick results on your phone in PDF form

 


Or print the result with a mini printer 

Results evaluation

Rapid hs-CRP/CRP tests may differ slightly from laboratory results - this is normal and does not indicate a faulty device. Use the following ranges to explain results clearly to customers and guide appropriate next steps. Reference ranges may vary slightly by lab and test method.

Result: Error / No control line

What it means: Test did not run correctly.

How to explain/action: Repeat the test. If the issue persists, check sample and instructions.

Result: 0 - 1 mg/L

What it means: Low risk, low inflammation - indicates low risk for cardiovascular disease.

How to explain/action: Reassure customer, suggest to maintain healthy lifestyle and routine health monitoring.

Result: 1 – 3 mg/L

What it means: Average risk, moderate inflammation - average risk for cardiovascular disease.

How to explain/action: Recommend healthy lifestyle changes and follow-up testing as well as consultation with a healthcare provider.

Result: > 3 mg/L

What it means: High risk, elevated inflammation - higher risk for cardiovascular disease or active inflammation/infection.

How to explain/action: Advise customer to consult healthcare provider for further evaluation and possible additional testing.

Key points to keep in mind:

  • Point-of-care results can differ slightly from lab tests. Small variations are common and do not mean the device is faulty.

  • If you see an error or no control line, the test might not have worked - always repeat.

  • For borderline or unusual values, advise customers to seek follow-up testing and medical advice instead of assuming device problems.

  • Ferritin levels can rise more slowly and stay elevated longer during inflammation compared to CRP. While CRP peaks early and drops quickly as inflammation resolves, ferritin may remain high even after CRP returns to normal. This is normal and should be considered when interpreting ferritin results.


Read more about hs-CRP, ferritin, and about results evaluation.

Disposal instructions

  • Dispose of used cassettes, pipettes, and lancets as biohazardous waste.
  • Do not reuse any test components.
  • Reader and adapter are reusable; clean according to the official maintenance guide.


Literature

  • Mayo clinic - C-reactive protein test

  • Medline Plus - C-reactive protein

  • Testing - hs-CRP Test (C-Reactive Protein High-Sensitivity)
  • Agency for Healthcare Research and Quality (AHRQ) - Assessing Cardiovascular Risk: Guideline Synthesis
  • Beyhoff N et al. Prognostic Impact of High-Sensitivity C-Reactive Protein in Patients Undergoing Percutaneous Coronary Intervention According to BMI. J Am Coll Cardiol Intv. 2020 Dec, 13 (24) 2882–2892.https://doi.org/10.1016/j.jcin.2020.09.024


Disclaimer

This information is educational and does not qualify for a medical advice. Always use local reference ranges and consult a healthcare professional for diagnosis and treatment.











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