How to perform test
hs-CRP/CRP | Wizbiotech
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Video tutorial for hs-CRP/CRP by Wizbiotech
Supples overview
- 1x CRP Test Cassette
- 1x Fixed-Volume Capillary Pipette
- 1x Sterile Lancet
- 1x Desinfection wipe
- 1x Buffer Solution Tube
- 1x Igloo Reader
- 1xWizbiotech Adapter
Included in test box:
- 1x CRP Test Cassette
- 1x Fixed-Volume Capillary Pipette
- 1x Buffer Solution Tube
Additionally needed to perform test:
- 1x Sterile Lancet
- 1x Desinfection wipe
- 1x Igloo Reader
- 1x Wizbiotech Adapter
Text instructions
STEP 1: Prepare and Disinfect the Sampling Area
Lay out all kit components. Disinfect the fingertip with the alcohol swab and let it dry.
Warm hands make blood sampling easier! Allow the test subject to warm their hands beforehand with a warm cloth, warm water, or by gently rubbing their hands together.
STEP 2: Perform a Fingerstick
Use the sterile lancet to puncture the side of the fingertip. Gently massage the finger to form a blood drop.
STEP 3: Remove the first droplet of blood
Wipe away the first drop of blood with a sterile swab before collecting the sample. This ensures accuracy and prevents contamination.
STEP 4: Collect exactly 10 µL of blood
The blood will fill the pipette automatically by capillary action.
Important: Ensure the blood sample is collected properly.
Important
Ensure that the pipette is completely filled without any bubbles. This will ensure that you obtain the exact 10 µL of blood required.
STEP 5: Insert blood collector into tube
Insert blood collector into buffer solution tube and close firmly.
STEP 6: Mix the blood with the buffer
Shake 5–10 times to ensure proper mixing.
Important
Make sure the blood and buffer are well mixed and show a uniform color.
STEP 7: Prepare the test cassette
Add 2 drops of the mixed sample into the test cassette
STEP 8: Start using the device
Turn on the device using the power button located underneath.
Once the device is on, press “New Measurement” and enter the required data to begin the test.
STEP 9: Insert the test cassette into the reader
Insert the test cassette into the reader — the measurement will start automatically.
STEP 10: Wait 3 minutes
STEP 11: Result is ready
When the timer ends, your result will be displayed on the screen.
Scan QR for quick results on your phone in PDF form
Or print the result with a mini printer
Results evaluation
Rapid hs-CRP/CRP tests may differ slightly from laboratory results - this is normal and does not indicate a faulty device. Use the following ranges to explain results clearly to customers and guide appropriate next steps. Reference ranges may vary slightly by lab and test method.
Result: Error / No control line / Invalid result
What it means: Test did not run correctly.
How to explain/action: Repeat the test. If the issue persists, check sample and instructions.
Result: <10 mg/L
What it means: Low risk, low inflammation - indicates low risk for cardiovascular disease.
How to explain/action: Reassure customer, suggest to maintain healthy lifestyle and routine health monitoring.
Result: >10 mg/L
What it means: Level ablove the normal CRP value, present risk for cardiovascular disease.
How to explain/action: Advise customer to consult healthcare provider for further evaluation and possible additional testing.
Key points to keep in mind:
If the measured CRP concentration of the sample is higher than the range of reference value, state such as physiological change or stress reaction should be excluded. It is indeed abnormal and should be diagnosed in combination with clinical symptoms. Above result is only for reference.
Test result of this method is only applicable to evaluation using the reference value established in this method and cannot be directly compared with result of other method. Point-of-care results can differ from lab tests. Small variations are common and do not mean the device is faulty.
Other factors that may cause wrong test result include technical reason, operation error and other sample factors.
- *Invalid result: If the assay result is invalid, the Igloo Reader Pro will display an "invalid" result. The test personnel should read the kit instructions and portable immunoassay analyzer instructions carefully and repeat the test. If the "invalid" result is obtained If it reappears, please contact the device manufacturer.
For borderline or unusual values, advise customers to seek follow-up testing and medical advice instead of assuming device problems.
Ferritin levels can rise more slowly and stay elevated longer during inflammation compared to CRP. While CRP peaks early and drops quickly as inflammation resolves, ferritin may remain high even after CRP returns to normal. This is normal and should be considered when interpreting ferritin results.

Read more about hs-CRP, ferritin, and about results evaluation.
Disposal instructions
- Dispose of used cassettes, pipettes, and lancets as biohazardous waste.
- Do not reuse any test components.
- Reader and adapter are reusable; clean according to the official maintenance guide.
Literature
- Sproston NR, Ashworth JJ. Role of C-Reactive Protein at Sites of Inflammation and Infection. Front Immunol. 2018;9:754. Published 2018 Apr 13.
- Ansar W, Ghosh S. Inflammation and Inflammatory Diseases, Markers, and Mediators: Role of CRP in Some Inflammatory Diseases. Biology of C Reactive Protein in Health and Disease. 2016;67-107. Published 2016 Mar 24.
- Mölkänen T, Ruotsalainen E, Rintala EM, Järvinen A. Predictive Value of C-Reactive Protein (CRP) in Identifying Fatal Outcome and Deep Infections in Staphylococcus aureus Bacteremia. PLoS One. 2016;11(5):e0155644. Published 2016 May 16.
Mayo clinic - C-reactive protein test
Medline Plus - C-reactive protein
- Testing - hs-CRP Test (C-Reactive Protein High-Sensitivity)
- Agency for Healthcare Research and Quality (AHRQ) - Assessing Cardiovascular Risk: Guideline Synthesis
- Beyhoff N et al. Prognostic Impact of High-Sensitivity C-Reactive Protein in Patients Undergoing Percutaneous Coronary Intervention According to BMI. J Am Coll Cardiol Intv. 2020 Dec, 13 (24) 2882–2892.https://doi.org/10.1016/j.jcin.2020.09.024
Disclaimer
This information is educational and does not qualify for a medical advice. Always use local reference ranges and consult a healthcare professional for diagnosis and treatment.